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Piero Parchi Selected Research

Codon (Codons)

10/2021Phenotypic diversity of genetic Creutzfeldt-Jakob disease: a histo-molecular-based classification.
11/2019Molecular Characterization of the Danish Prion Diseases Cohort With Special Emphasis on Rare and Unique Cases.
1/2019Two distinct prions in fatal familial insomnia and its sporadic form.
1/2019Age at onset in genetic prion disease and the design of preventive clinical trials.
12/2018Age at onset of genetic (E200K) and sporadic Creutzfeldt-Jakob diseases is modulated by the CYP4X1 gene.
11/2017Atypical Creutzfeldt-Jakob disease with PrP-amyloid plaques in white matter: molecular characterization and transmission to bank voles show the M1 strain signature.
6/2016Neuropathological and biochemical criteria to identify acquired Creutzfeldt-Jakob disease among presumed sporadic cases.
1/2016Distinctive properties of plaque-type dura mater graft-associated Creutzfeldt-Jakob disease in cell-protein misfolding cyclic amplification.
4/2015Transmission properties of atypical Creutzfeldt-Jakob disease: a clue to disease etiology?
10/2012Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA.
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Piero Parchi Research Topics

Disease

44Prion Diseases (Transmissible Spongiform Encephalopathies)
10/2022 - 03/2003
34Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
01/2022 - 10/2003
21Dementia (Dementias)
01/2022 - 01/2008
18Sporadic Creutzfeldt-Jakob Disease
02/2022 - 04/2003
18Alzheimer Disease (Alzheimer's Disease)
01/2022 - 03/2003
16Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 10/2003
15Acquired CJD
01/2020 - 01/2003
7Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
01/2021 - 07/2015
7Sleep Initiation and Maintenance Disorders (Insomnia)
11/2019 - 01/2003
6Fatal Familial Insomnia
01/2019 - 10/2004
6Amyloid Plaque
01/2018 - 02/2010
5Disease Progression
01/2021 - 04/2013
5Scrapie
01/2018 - 10/2003
5Kuru
11/2017 - 10/2010
4Parkinson Disease (Parkinson's Disease)
10/2021 - 01/2008
3Gliosis
02/2022 - 01/2018
3Cognitive Dysfunction
01/2022 - 01/2021
3Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
10/2020 - 01/2020
3Neuroinflammatory Diseases
06/2020 - 12/2019
3Tauopathies
01/2020 - 01/2018
3Frontotemporal Dementia (Semantic Dementia)
01/2020 - 01/2018
3Corticobasal Degeneration
01/2020 - 01/2017
3Synucleinopathies
01/2020 - 01/2008
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2022 - 06/2020
2Parkinsonian Disorders (Parkinsonism)
10/2021 - 01/2020
2Lewy Body Disease (Lewy Body Dementia)
01/2021 - 01/2008
2Narcolepsy
01/2020 - 06/2014
2Proteostasis Deficiencies
01/2019 - 01/2018
2Amyloidosis
06/2018 - 02/2010
2Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
01/2018 - 02/2010
2Myoclonus (Nocturnal Myoclonus)
01/2018 - 10/2009
2Infections
01/2011 - 01/2010
1Orthostatic Hypotension (Postural Hypotension)
10/2021
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
01/2021
1Autoimmune Diseases of the Nervous System
01/2021
1Pick Disease of the Brain (Pick's Disease)
01/2020
1Normal Pressure Hydrocephalus
01/2019
1Peripheral Nervous System Diseases (PNS Diseases)
01/2019
1Olivary Degeneration
01/2019
1Neurologic Manifestations (Neurological Manifestations)
01/2018
1Ataxia (Dyssynergia)
01/2018
1Rare Diseases (Rare Disease)
11/2017

Drug/Important Bio-Agent (IBA)

49Prion ProteinsIBA
01/2022 - 04/2003
34PrionsIBA
01/2022 - 03/2003
23Biomarkers (Surrogate Marker)IBA
01/2022 - 05/2013
22Codon (Codons)IBA
10/2021 - 01/2003
21Proteins (Proteins, Gene)FDA Link
01/2022 - 06/2014
13Methionine (L-Methionine)FDA Link
10/2021 - 09/2006
12Peptide Hydrolases (Proteases)FDA Link
10/2022 - 01/2003
11Valine (L-Valine)FDA Link
10/2021 - 09/2006
10SynucleinsIBA
01/2022 - 01/2008
6Amyloid (Amyloid Fibrils)IBA
01/2022 - 02/2010
5diazonaphthalenedisulfonic acid (NDS)IBA
01/2022 - 11/2018
5Protein Isoforms (Isoforms)IBA
01/2020 - 10/2003
4Biological ProductsIBA
01/2021 - 01/2011
4Endopeptidase K (Proteinase K)IBA
01/2018 - 10/2003
3Amyloid beta-PeptidesIBA
10/2021 - 10/2008
314-3-3 Proteins (14-3-3 Protein)IBA
11/2020 - 04/2015
3AntibodiesIBA
11/2014 - 11/2007
2Peptides (Polypeptides)IBA
02/2022 - 12/2019
2Apolipoproteins E (ApoE)IBA
01/2022 - 01/2019
2ProgranulinsIBA
01/2021 - 01/2017
2tau Proteins (tau Protein)IBA
10/2020 - 01/2020
2Amyloidogenic ProteinsIBA
01/2020 - 01/2020
2Protein AggregatesIBA
12/2019 - 11/2008
2ImmunosorbentsIBA
12/2019 - 11/2018
2EnzymesIBA
12/2019 - 11/2018
2PrPSc ProteinsIBA
11/2014 - 04/2013
1preproenkephalinIBA
02/2022
1proenkephalinIBA
02/2022
1antineoplaston A10 (A 10)IBA
01/2022
1alpha-SynucleinIBA
10/2021
1LDL Receptors (LDL Receptor)IBA
01/2021
1SphingolipidsIBA
10/2020
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2020
1N 30IBA
01/2020
1UbiquitinIBA
01/2020
1chitotriosidaseIBA
12/2019
1Glial Fibrillary Acidic ProteinIBA
12/2019
1Chitinase-3-Like Protein 1IBA
12/2019
1Indicators and Reagents (Reagents)IBA
12/2019
1RNA (Ribonucleic Acid)IBA
07/2019
1Pharmaceutical PreparationsIBA
01/2019
1Aspartic Acid (Aspartate)FDA Link
01/2019
1AsparagineIBA
01/2019
1ApolipoproteinsIBA
01/2019
1SerpinsIBA
01/2018
1Amino AcidsFDA Link
01/2018
1thioflavin TIBA
01/2018
1Growth Hormone (Somatotropin)IBA
01/2018
1Presenilin-1IBA
01/2018
1Adenosine Monophosphate (AMP)IBA
01/2018
1Protein Kinases (Protein Kinase)IBA
01/2018
1Presenilin-2IBA
01/2018
1GranulinsIBA
01/2018
1CeroidIBA
01/2017
1LipofuscinIBA
01/2017

Therapy/Procedure

2Therapeutics
12/2019 - 01/2019
1Precision Medicine
01/2021
1Transplantation
01/2019